Major Four Herb Combination (tonifying and replenishing formula) EFFECTS: fortifying the spleen and nourishing the stomach; tonifying qi and harmonizing the middle. INDICATION: spleen-stomach qi deficiency; neurasthenia; anemia; dyspepsia; pale complexion; inappetence and sloppy stool; amyosthenia; weak pulse; shock after hemorrhea. CLINICAL REFERENCE: This formula is often used in invigorating the stomach and treating gastroenteritis, gastric ulcer, chronic hepatitis, senile chronic bronchitis, and leukopenia . It can enhance immunity.